Scientific programme

Journal of Internal Medicine Symposium:

MITOCHONDRIA IN HUMAN DISEASE

 

Time: September 16-18, 2019 (lunch-lunch)
Venue: Vår Gård, Saltsjöbaden, Stockholm, Sweden.
Participants: 150

 

Programme

 

Day 1 – 16 September 2019

12:00-13:30 Lunch and registration
13:45-14:00 Welcome and introductory remarks

Nils-Göran Larsson and Anna Wedell, Karolinska Institutet
Ulf de Faire, Journal of Internal Medicine.

Session 1: MECHANISMS IN MITOCHONDRIAL DISEASE
Chair: Nils-Göran Larsson, Karolinska Institutet, Stockholm, Sweden
14:00-14:30 Mitochondrial disease phenotypes in children
Shamima Rahman, Great Ormond Street Hospital, London, UK
14:30-15:00 Mitochondrial RNA processing in disease
Aleksandra Filipovska, University of Western Australia, Perth, Australia
15:00-15:15 Poster talk 1
15:15-15:30 Poster talk 2
15:30-16:00 Coffee break
16:00-16:30 Mitochondrial disease and optic atrophy
Valerio Carelli, University of Bologna, Italy
16:30-17:00 Malfunction of the mitochondrial replisome and mtDNA mutations
Maria Falkenberg, Göteborgs Universitet, Sweden
17:00-17:30 Principles of human mtDNA inheritance
Patrick Chinnery, University of Cambridge, UK
17:30- 19.30 Dinner
Session 2: REGULATION OF MITOCHONDRIAL FUNCTION
Chair: Anna Wedell, Karolinska Institutet, Stockholm, Sweden
19:30-20:00 Mitochondrial import of S-adenosyl methionine and the mitochondrial methylproteome
Anna Wredenberg, Karolinska Institutet, Sweden
20:00-20.30 The in vivo role of mitophagy
Ian Ganley, University of Dundee, UK
20.30-22.00 Poster session and drinks

Day 2 – 17 September 2019

Session 3: THE ARCHITECTURE OF MITOCHONDRIA
Chair: Nils-Göran Larsson, Karolinska Instiutet, Sweden
09:00-09:30 Protein complexes organizing mitochondrial compartments
Klaus Pfanner, University of Freiburg, Germany
09:30-09:45 Poster talk 3
09.45-10:00 Poster talk 4
10:00-10:30 Structures of respiratory chain complexes and supercomplexes
Judy Hirst, Mitochondrial Biology Unit, MRC, Cambridge
10:30-11:00 Coffee break
11:00-11:30 Superresolution microscopy of mitochondrial organization and dynamics
Stefan Jakobs, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
11.30-12.00 Electron cryo-tomography of protein complexes in mitochondrial membranes
Werner Kühlbrandt, Max Planck Institute for Biophysics, Frankfurt, Germany
12:00-13:00 Lunch
13:30-17:30 Excursion with guided tour of the Nobel museum and visit of the old town “Gamla Stan” in Stockholm.
17:30-19:30 Dinner
Session 4: MITOCHONDRIAL TRANSLATION
Chair: Anna Wredenberg, Karolinska Institutet, Stockholm, Sweden
19:30-20:00 Coordination of mitochondrial translation and respiratory chain assembly
Martin Ott, Stockholm University, Sweden
20:00-20:15 Poster talk 5
20.15-20:30 Poster talk 6
20:30-21:00 Biogenesis of the mammalian mitochondrial ribosome
Joanna Rorbach, Karolinska Institutet, Sweden
21:00 Poster sessions and drinks

Day 3 – 18 September 2019

Session 5: TREATMENT OF MITOCHONDRIAL DYSFUNCTION
Chair: Claes Gustafsson, Göteborgs Universitet, Göteborg, Sweden
09:00-09:30 Gene therapy by enzymatic editing of mtDNA in the mouse
Carlos Moraes, University of Miami, Miami, USA
09:30-10:00 Cellular responses in mitochondrial disease
Anu Suomalainen, University of Helsinki, Finland
10:00-10:15 Poster talk 7
10:15-10:30 Poster talk 8
10:30-11.00 Coffee
11:00-11:30 Nuclear effects caused by mutated cytochrome c oxidase
Ann Saada, Hadassah Medical Center, Jerusalem, Israel
11:30-12:00 Strategies for treatment of mitochondrial disease
Massimo Zeviani, Mitochondrial Biology Unit, MRC, Cambridge
12:00-12:30 Reproductive options for women with mitochondrial DNA mutations
Doug Turnbull, University of Newcastle, Newcastle, UK
12:30-14:00 Lunch and departure

Hosted by

Important dates

Abstract submission dead-line May 31

Notification June 10 

Deadline registration for the Symposium June 14

Professional Conference Organizer

For general information, kindly contact:
mitochondria2019@akademikonferens.se

Akademikonferens +46 18 67 15 33 or the switchboard +46 18 67 10 03

For scientific content and abstracts, kindly contact: Virpi.Tohonen@ki.se

www.akademikonferens.se